|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
RGS Proteins
|
|
Descriptor Spanish:
|
|
Proteínas RGS
|
|
Descriptor Portuguese:
|
|
Proteínas RGS
|
|
Synonyms English:
|
|
RGS Protein (G-Protein Signaling)
Regulators of G Protein Signaling Proteins
Regulators of G-Protein Signaling Proteins
|
|
Tree Number:
|
|
D12.644.360.325.150.750
D12.776.476.325.150.750
|
|
Definition English:
|
|
A large family of evolutionarily conserved proteins that function as negative regulators of HETEROTRIMERIC GTP-BINDING PROTEINS. RGS PROTEINS act by increasing the GTPase activity of the G alpha subunit of a heterotrimeric GTP-binding protein, causing it to revert to its inactive (GDP-bound) form. |
|
Indexing Annotation English:
|
|
do not confuse with GTP-BINDING PROTEIN REGULATORS; not the same as RGS tripeptide
|
|
Pharmacological Action:
|
|
GTP Phosphohydrolase Activators
|
|
History Note English:
|
|
2000; for RGS PROTEIN (G-PROTEIN SIGNALING) use GTPASE-ACTIVATING PROTEINS (NM) 1997-1999
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
34487
|
|
Unique Identifier:
|
|
D020710
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS
|